Onatasertib (CC 223)
Onatasertib (CC 223) is a potent, selective, and orally bioavailable mTOR inhibitor with IC50 of 16 nM, >200-fold selectivity over the related PI3K-α. Phase 1/2.
Trivial name | ATG-008 |
Catalog Number | S7886 |
Molecular Formula | C21H27N5O3 |
CAS# | 1228013-30-6 |
Inchi | InChI=1S/C21H27N5O3/c1-21(2,28)17-9-4-13(10-22-17)16-11-23-19-20(25-16)26(18(27)12-24-19)14-5-7-15(29-3)8-6-14/h4,9-11,14-15,28H,5-8,12H2,1-3H3,(H,23,24)/t14-,15- |
Inchi Key | UFKLYTOEMRFKAD-SHTZXODSSA-N |
SMILES | CC(C)(C1=NC=C(C=C1)C2=CN=C3C(=N2)N(C(=O)CN3)C4CCC(CC4)OC)O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/cc-223.html |
Additional Information | https://file.selleck.cn/downloads/struct/cc-223-chemical-structure-selleck.gif |