Marinopyrrole A (Maritoclax)

Marinopyrrole A (Maritoclax) is a selective Mcl-1 antagonist. It binds to Mcl-1, but not Bcl-XL, and targets Mcl-1 for proteasomal degradation. Maritoclax disrupts the interaction between Bim and Mcl-1 with an IC50 of 10.1 μM.

Trivial name N/A
Catalog Number S7126
Molecular Formula C22H12Cl4N2O4
CAS# 1227962-62-0
Inchi InChI=1S/C22H12Cl4N2O4/c23-12-9-13(19(31)10-5-1-3-7-14(10)29)28(22(12)26)18-16(24)21(25)27-17(18)20(32)11-6-2-4-8-15(11)30/h1-9,27,29-30H
Inchi Key QYPJBTMRYKRTFG-UHFFFAOYSA-N
SMILES C1=CC=C(C(=C1)C(=O)C2=CC(=C(N2C3=C(NC(=C3Cl)Cl)C(=O)C4=CC=CC=C4O)Cl)Cl)O
Size 5mg
Supplier Page http://www.selleckchem.com/products/marinopyrrole-a-maritoclax.html
Additional Information https://file.selleck.cn/downloads/struct/marinopyrrole-a-chemical-structure-s7126.gif