Thiazovivin

Cell-permeable. Helps in promoting human embryonic stem cell (hESC) survival by > 30-fold. Thiazovivin enhances the efficiency of fibroblast reprogramming to generate induced pluripotent stem cells (iPSCs) when used in combination with SB-431542 and PD 0325901. Acts as a Rho-associated Kinase (ROCK) inhibitor. Tzv (2 µM) inhibits ROCK activity and protect hESCs at a similar level as Y-27632 (10 µM), a well-known, selective ROCK inhibitor.

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Catalog Number	ABS-067
Alternative Name(s)	N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide; Tzv
CAS#	1226056-71-8
Inchi	InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13-6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20)
Inchi Key	DOBKQCZBPPCLEG-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)CNC(=O)C2=CSC(=N2)NC3=NC=NC=C3
Size	Inquiry
Supplier Page	https://www.agingclocks.com/thiazovivin-item-1531.html