Sapanisertib (MLN0128)

Sapanisertib (MLN0128, INK 128, TAK-228) is a potent and selective mTOR inhibitor with IC50 of 1 nM in cell-free assays; >200-fold less potent to class I PI3K isoforms, superior in blocking mTORC1/2 and sensitive to pro-invasion genes (vs Rapamycin). Phase 1.

Price Not Available 5mg Sapanisertib (MLN0128) Supplier Page

Trivial name	INK 128,TAK-228
Catalog Number	S2811
Molecular Formula	C15H15N7O
CAS#	1224844-38-5
Inchi	InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)
Inchi Key	GYLDXIAOMVERTK-UHFFFAOYSA-N
SMILES	CC(C)N1C2=NC=NC(=C2C(=N1)C3=CC4=C(C=C3)OC(=N4)N)N
Size	5mg
Supplier Page	http://www.selleckchem.com/products/ink128.html
Additional Information	https://file.selleck.cn/downloads/struct/INK-128-chemical-structure-s2811.gif