Rosiglitazone
Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action. Rosiglitazone modulates TRP channels and induces autophagy. Rosiglitazone prevents ferroptosis.
| Trivial name | BRL 49653 |
| Catalog Number | S2556 |
| Molecular Formula | C18H19N3O3S |
| CAS# | 122320-73-4 |
| Inchi | InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23) |
| Inchi Key | YASAKCUCGLMORW-UHFFFAOYSA-N |
| SMILES | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3 |
| Size | 200mg |
| Supplier Page | http://www.selleckchem.com/products/Rosiglitazone-Avandia.html |
| Additional Information | https://file.selleck.cn/downloads/struct/Rosiglitazone-Avandia-chemical-structure-S2556.gif |