AT791
AT791 is a potent and orally bioavailable inhibitor of TLR7 and TLR9 with an IC50 of 3.33 μM and 0.04 μM, respectively, in human embryonic kidney cells and also inhibits DNA-TLR9 interaction in vitro.
| Catalog Number | E5812 |
| Molecular Formula | C20H16N2O4 |
| CAS# | 1219962-49-8 |
| Inchi | InChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1 |
| Inchi Key | VSJKWCGYPAHWDS-FQEVSTJZSA-N |
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/at791.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5812-AT791-chemical-structure.png |