AT791
AT791 is a potent and orally bioavailable inhibitor of TLR7 and TLR9 with an IC50 of 3.33 μM and 0.04 μM, respectively, in human embryonic kidney cells and also inhibits DNA-TLR9 interaction in vitro.
| Catalog Number | E5812 |
| Molecular Formula | C11H16FN3O3 |
| CAS# | 1219962-49-8 |
| Inchi | InChI=1S/C11H16FN3O3/c1-2-3-4-5-6-13-10(17)15-7-8(12)9(16)14-11(15)18/h7H,2-6H2,1H3,(H,13,17)(H,14,16,18) |
| Inchi Key | AOCCBINRVIKJHY-UHFFFAOYSA-N |
| SMILES | CCCCCCNC(=O)N1C=C(C(=O)NC1=O)F |
| Size | 1g |
| Supplier Page | http://www.selleckchem.com/products/at791.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5812-AT791-chemical-structure.png |