Aurothioglucose
Aurothioglucose (Gold thioglucose), containing monovalent gold ion, is a potent active-site inhibitor of TrxR1 (thioredoxin reductase 1), with an IC50 of 65 nM. Aurothioglucose inhibits the DNA binding of NF-κB in vitro. Aurothioglucose shows anti-HIV and anti-rheumatic activities.
| Trivial name | Gold thioglucose |
| Catalog Number | E7941 |
| Molecular Formula | C25H23F3N4O2 |
| CAS# | 12192-57-3 |
| Inchi | InChI=1S/C25H23F3N4O2/c26-25(27,28)21-9-4-20(5-10-21)8-13-24-30-22(18-34-24)17-33-23-11-6-19(7-12-23)3-1-2-15-32-16-14-29-31-32/h4-14,16,18H,1-3,15,17H2/b13-8+ |
| Inchi Key | ZTFBIUXIQYRUNT-MDWZMJQESA-N |
| SMILES | C1=CC(=CC=C1CCCCN2C=CN=N2)OCC3=COC(=N3)C=CC4=CC=C(C=C4)C(F)(F)F |
| Size | 1mg |
| Supplier Page | http://www.selleckchem.com/products/aurothioglucose.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7941-aurothioglucose-chemical-structure-tube.png |