Setanaxib (GKT137831)

Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.

Price Not Available 1g Setanaxib (GKT137831) Supplier Page

Trivial name	GKT831
Catalog Number	S7171
Molecular Formula	C21H19ClN4O2
CAS#	1218942-37-0
Inchi	InChI=1S/C21H19ClN4O2/c1-24(2)14-8-6-7-13(11-14)20-19-16(12-18(27)25(20)3)23-26(21(19)28)17-10-5-4-9-15(17)22/h4-12,23H,1-3H3
Inchi Key	RGYQPQARIQKJKH-UHFFFAOYSA-N
SMILES	CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl
Size	1g
Supplier Page	http://www.selleckchem.com/products/gkt137831.html
Additional Information	https://file.selleck.cn/downloads/struct/gkt137831-chemical-structure-s7171.gif