Setanaxib (GKT137831)

Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.

Price Not Available 10mM/1mL Setanaxib (GKT137831) Supplier Page

Trivial name	GKT831
Catalog Number	S7171
Molecular Formula	C21H19ClN4O2
CAS#	1218942-37-0
Inchi	InChI=1S/C21H19ClN4O2/c1-24(2)14-8-6-7-13(11-14)20-19-16(12-18(27)25(20)3)23-26(21(19)28)17-10-5-4-9-15(17)22/h4-12,23H,1-3H3
Inchi Key	RGYQPQARIQKJKH-UHFFFAOYSA-N
SMILES	CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl
Size	10mM/1mL
Supplier Page	http://www.selleckchem.com/products/gkt137831.html
Additional Information	https://file.selleck.cn/downloads/struct/gkt137831-chemical-structure-s7171.gif