Setanaxib (GKT137831)

Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.

Price Not Available 100mg Setanaxib (GKT137831) Supplier Page
Trivial name GKT831
Catalog Number S7171
Molecular Formula C21H19ClN4O2
CAS# 1218942-37-0
Inchi InChI=1S/C21H19ClN4O2/c1-24(2)14-8-6-7-13(11-14)20-19-16(12-18(27)25(20)3)23-26(21(19)28)17-10-5-4-9-15(17)22/h4-12,23H,1-3H3
Inchi Key RGYQPQARIQKJKH-UHFFFAOYSA-N
SMILES CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl
Size 100mg
Supplier Page http://www.selleckchem.com/products/gkt137831.html
Additional Information https://file.selleck.cn/downloads/struct/gkt137831-chemical-structure-s7171.gif