Alpelisib (BYL719)
Alpelisib (BYL719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2814 |
| Molecular Formula | C30H22F6N6O5 |
| CAS# | 1217486-61-7 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | FC(F)(F)OC1=CC=C2[NH]C(=NC2=C1)C3=NC=C(OCCOCCOC4=CN=C(C=C4)C5=NC6=C([NH]5)C=CC(=C6)OC(F)(F)F)C=C3 |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/byl719.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BYL-719-chemical-structure-s2814.gif |