Alpelisib (BYL719)
Alpelisib (BYL719) is a potent and selective PI3Kα inhibitor with IC50 of 5 nM in a cell-free assay, and minimal effect on PI3Kβ/γ/δ. Phase 2.
| Trivial name | N/A |
| Catalog Number | S2814 |
| Molecular Formula | C19H22F3N5O2S |
| CAS# | 1217486-61-7 |
| Inchi | InChI=1S/C19H22F3N5O2S/c1-10-14(11-6-7-24-13(9-11)18(2,3)19(20,21)22)30-16(25-10)26-17(29)27-8-4-5-12(27)15(23)28/h6-7,9,12H,4-5,8H2,1-3H3,(H2,23,28)(H,25,26,29)/t12-/m0/s1 |
| Inchi Key | STUWGJZDJHPWGZ-LBPRGKRZSA-N |
| SMILES | CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/byl719.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BYL-719-chemical-structure-s2814.gif |