GSK4112
GSK4112 is a functional Rev-erbα agonist with an EC50 of 0.4 μM. It represses the expression of gluconeogenic genes in liver cells and reduces glucose output in primary hepatocytes.
| Trivial name | N/A |
| Catalog Number | S5182 |
| Molecular Formula | C37H42N2O6 |
| CAS# | 1216744-19-2 |
| Inchi | InChI=1S/C37H42N2O6/c1-38-15-13-26-20-36(43-4)37(44-5)22-29(26)30(38)16-23-6-9-27(10-7-23)45-35-18-24(8-11-32(35)40)17-31-28-21-33(41)34(42-3)19-25(28)12-14-39(31)2/h6-11,18-22,30-31,40-41H,12-17H2,1- 5H3/t30-,31-/m1/s1 |
| Inchi Key | BURJAQFYNVMZDV-FIRIVFDPSA-N |
| SMILES | CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)O)O)OC)OC |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/gsk4112.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gsk4112-chemical-structure-s5182.gif |