APY29
APY29 is a type I kinase inhibitor of IRE1α that binds to the ATP-binding site on IRE1α and inhibits its autophosphorylation (IC50 = 280 nM) and enhances its RNase function (EC50 = 460 nM).
| Trivial name | N/A |
| Catalog Number | S6623 |
| Molecular Formula | C17H16N8 |
| CAS# | 1216665-49-4 |
| Inchi | InChI=1S/C17H16N8/c1-2-10(1)13-8-16(25-24-13)22-15-5-6-18-17(23-15)21-11-3-4-12-14(7-11)20-9-19-12/h3-10H,1-2H2,(H,19,20)(H3,18,21,22,23,24,25) |
| Inchi Key | WJNBSTLIALIIEW-UHFFFAOYSA-N |
| SMILES | C1CC1C2=CC(=NN2)NC3=NC(=NC=C3)NC4=CC5=C(C=C4)N=CN5 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/apy29.html |
| Additional Information | https://file.selleck.cn/downloads/struct/apy29-chemical-structure-s6623.gif |