PCLX-001 (DDD86481)
PCLX-001 (DDD86481) is an orally active dual N-myristoyltransferase (NMT) inhibitor. It inhibits NMT1 and NMT2 with IC50 of 5 nM and 8 nM, respectively, in vitro. PCLX-001 inhibits early B-cell receptor (BCR) signalling, which can be used in B-cell malignancy research.
Trivial name | DDD86481 |
Catalog Number | E1217 |
Molecular Formula | C24H30Cl2N6O2S |
CAS# | 1215011-08-7 |
Size | 100mg |
Supplier Page | http://www.selleckchem.com/products/pclx-001-ddd86481.html |
Additional Information | https://file.selleck.cn/downloads/struct/e1217-PCLX-001-DDD86481-chemical-structure.png |