DDD85646
DDD85646 (IMP-366) is an orally active inhibitor of N-myristoyltransferase(NMT), with an IC50 of 2 nM for Trypanosoma brucei NMT (TbNMT) and 4 nM for human NMT (hNMT). It exhibits a potential for treating human African trypanosomiasis.
| Trivial name | IMP-366 |
| Catalog Number | E5974 |
| Molecular Formula | C19H16N6O4S |
| CAS# | 1215010-55-1 |
| Inchi | InChI=1S/C19H16N6O4S/c1-12-10-21-17(19(23-12)28-2)25-30(26,27)15-4-3-9-20-16(15)13-5-7-14(8-6-13)18-24-22-11-29-18/h3-11H,1-2H3,(H,21,25) |
| Inchi Key | FJHHZXWJVIEFGJ-UHFFFAOYSA-N |
| SMILES | CC1=CN=C(C(=N1)OC)NS(=O)(=O)C2=C(N=CC=C2)C3=CC=C(C=C3)C4=NN=CO4 |
| Size | 100mg |
| Supplier Page | http://www.selleckchem.com/products/ddd85646.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E5974-DDD85646-chemical-structure.png |