Amylin (14-20) (human)
The formation of amyloid deposits by IAPP could play a central role in the pathogenesis of type II diabetes. Besides the amyloidogenic 20-29 region, the domain NFLVHSS (IAPP 14-20) tends to aggregate and seems to be involved in plaque formation. The peptide NFLVHSS (IAPP 14-20) tends to aggregate and seems to be involved in plaque formation.
| Catalog Number | A12019 |
| Alternative Name(s) | L-asparagyl-L-phenylalanyl-L-leucyl-L-valyl-L-histidyl-L-seryl-L-serine |
| Molecular Formula | C36H54N10O11 |
| CAS# | 121341-77-3 |
| Purity | >95% |
| Inchi | InChI=1S/C36H54N10O11/c1-18(2)10-23(42-31(51)24(11-20-8-6-5-7-9-20)41-30(50)22(37)13-28(38)49)33(53)46-29(19(3)4)35(55)43-25(12-21-14-39-17-40-21)32(52)44-26(15-47)34(54)45-27(16-48)36(56)57/h5-9,14,17-19,22-27,29,47-48H,10-13,15-16,37H2,1-4H3,(H2,38,49)(H,39,40)(H,41,50)(H,42,51)(H,43,55)(H,44,52)(H,45,54)(H,46,53)(H,56,57)/t22-,23-,24-,25-,26-,27-,29-/m0/s1 |
| Inchi Key | NYWRQILLKJSDDP-UIRCOLITSA-N |
| SMILES | CC(C)C[C@@H](C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(=O)N)N |
| Size | Inquiry |
| Supplier Page | https://www.creative-peptides.com/product/amylin-14-20-human-item-a12019-41056.html |