WZ4002
WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with IC50 of 2 nM/8 nM in BaF3 cell line; does not inhibit ERBB2 phosphorylation (T798I).
| Trivial name | N/A |
| Catalog Number | S1173 |
| Molecular Formula | C25H27ClN6O3 |
| CAS# | 1213269-23-8 |
| Inchi | InChI=1S/C25H27ClN6O3/c1-4-23(33)28-17-6-5-7-19(14-17)35-24-20(26)16-27-25(30-24)29-21-9-8-18(15-22(21)34-3)32-12-10-31(2)11-13-32/h4-9,14-16H,1,10-13H2,2-3H3,(H,28,33)(H,27,29,30) |
| Inchi Key | ITTRLTNMFYIYPA-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)C2=CC(=C(C=C2)NC3=NC=C(C(=N3)OC4=CC=CC(=C4)NC(=O)C=C)Cl)OC |
| Size | 10mg |
| Supplier Page | http://www.selleckchem.com/products/WZ4002.html |
| Additional Information | https://file.selleck.cn/downloads/struct/WZ4002-chemical-structure-S1173.gif |