Solcitinib
Solcitinib (GLPG0778, GSK2586184) is an inhibitor of JAK1 with an IC50 of 8-9 nM, and shows 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively.
| Trivial name | GLPG0778, GSK2586184 |
| Catalog Number | S5917 |
| Molecular Formula | C51H63F2N11O10 |
| CAS# | 1206163-45-2 |
| Inchi | #N/A |
| Inchi Key | #N/A |
| SMILES | CNC(=O)N1CCC2=C(C1)C(=N[N]2C3CCN(CC3)C(=O)CCOCCOCCOCCOCCNC4=CC=C5C(=O)N(C6CCC(=O)NC6=O)C(=O)C5=C4)N7CCCC8=CC(=C(C=C78)C(F)F)C9=C[N](C)N=C9 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/solcitinib.html |
| Additional Information | https://file.selleck.cn/downloads/struct/solcitinib-chemical-structure-s5917.gif |