GLPG0634 analogue
GLPG0634 analogue is a selective JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM, and 116 nM for JAK1, JAK2, JAK3, and TYK2, respectively. Phase 2.
Trivial name | N/A |
Catalog Number | S7137 |
Molecular Formula | C23H18N6O2 |
CAS# | 1206101-20-3 |
Inchi | InChI=1S/C23H18N6O2/c24-12-18-9-4-15(13-25-18)14-31-19-10-7-16(8-11-19)20-2-1-3-21-26-23(28-29(20)21)27-22(30)17-5-6-17/h1-4,7-11,13,17H,5-6,14H2,(H,27,28,30) |
Inchi Key | QZXABVVSCDZCLR-UHFFFAOYSA-N |
SMILES | C1CC1C(=O)NC2=NN3C(=N2)C=CC=C3C4=CC=C(C=C4)CN5CCS(=O)(=O)CC5 |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/glpg0634.html |
Additional Information | https://file.selleck.cn/downloads/struct/GLPG0634-chemical-structure-s7137.gif |