Epacadostat (INCB024360)
Epacadostat (INCB024360) is a potent and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor with IC50 of 10 nM and displays high selectivity over other related enzymes such as IDO2 or tryptophan 2,3-dioxygenase (TDO).
Trivial name | N/A |
Catalog Number | S7910 |
Molecular Formula | C11H13BrFN7O4S |
CAS# | 1204669-58-8 |
Inchi | InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16,21H,3-4H2,(H,15,20)(H,17,18)(H2,14,22,23) |
Inchi Key | FBKMWOJEPMPVTQ-UHFFFAOYSA-N |
SMILES | C1=CC(=C(C=C1N=C(C2=NON=C2NCCNS(=O)(=O)N)NO)Br)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/epacadostat-incb024360.html |
Additional Information | https://file.selleck.cn/downloads/struct/epacadostat-incb024360-chemical-structure-s7910.gif |