AZD1208
AZD1208 is a potent, and orally available Pim kinase inhibitor with IC50 of 0.4 nM, 5 nM, and 1.9 nM for Pim1, Pim2, and Pim3 in cell-free assays, respectively. AZD1208 induces autophagy, cell cycle arrest and apoptosis. Phase 1.
| Trivial name | N/A |
| Catalog Number | S7104 |
| Molecular Formula | C21H21N3O2S |
| CAS# | 1204144-28-4 |
| Inchi | InChI=1S/C21H21N3O2S/c22-16-9-5-11-24(13-16)19-15(12-18-20(25)23-21(26)27-18)8-4-10-17(19)14-6-2-1-3-7-14/h1-4,6-8,10,12,16H,5,9,11,13,22H2,(H,23,25,26)/b18-12-/t16-/m1/s1 |
| Inchi Key | MCUJKPPARUPFJM-UWCCDQBKSA-N |
| SMILES | C1CC(CN(C1)C2=C(C=CC=C2C3=CC=CC=C3)C=C4C(=O)NC(=O)S4)N |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/azd-1208.html |
| Additional Information | https://file.selleck.cn/downloads/struct/AZD1208-chemical-structure-s7104.gif |