Spebrutinib (AVL-292)

Spebrutinib (AVL-292) is a covalent, orally active, and highly selective BTK inhibitor with IC50 of <0.5 nM, displaying at least 1400-fold selectivity over the other kinases assayed. Phase 1.

Price Not Available 1g Spebrutinib (AVL-292) Supplier Page

Trivial name	CC-292
Catalog Number	S7173
Molecular Formula	C22H22FN5O3
CAS#	1202757-89-8
Inchi	InChI=1S/C22H22FN5O3/c1-3-20(29)25-16-5-4-6-17(13-16)26-21-19(23)14-24-22(28-21)27-15-7-9-18(10-8-15)31-12-11-30-2/h3-10,13-14H,1,11-12H2,2H3,(H,25,29)(H2,24,26,27,28)
Inchi Key	KXBDTLQSDKGAEB-UHFFFAOYSA-N
SMILES	COCCOC1=CC=C(C=C1)NC2=NC=C(C(=N2)NC3=CC(=CC=C3)NC(=O)C=C)F
Size	1g
Supplier Page	http://www.selleckchem.com/products/avl-292.html
Additional Information	https://file.selleck.cn/downloads/struct/AVL-292-chemical-structure-s7173.gif