Scoparone is isolated from Artemisia capillaris Thunb., has anticoagulant, vasorelaxant antioxidant, anti-inflammatory activities.In Vitro: Scoparone (0-0.4 nM; 24-48 hours) produces the most inhibition on PSC proliferation at 0.4 nM.In Vivo: Scoparone (oral administration; 30 mg/kg, 60 mg/kg; 4 weeks) greatly ameliorates the pancreatic weight loss induced by DBTC in pancreatitis rats.