(5E)-7-Oxozeaenol
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM).1 (5E)-7-Oxozeaenol inhibits proliferation of MCF-7, H460, SF-268, HT-29, and MDA-MB-435 human cancer cells with IC50 values of 4.9, 1.2, 5.6, 4.4, and 5.5 μM, respectively.2
![](https://smallmolecules.com/sm/wp-content/uploads/products/targetmol/wk/wkgfd2nrgs2exm-waaaaactmn6k651.jpg)
Catalog Number | T35438 |
Molecular Formula | C19H22O7 |
CAS# | 1198574-97-8 |
SMILES | OC1=C2C(=CC(OC)=C1)/C=C/C[C@H](O)[C@H](O)C(=O)\C=C\C[C@H](C)OC2=O |
Size | 10 mg |
Supplier Page | https://www.targetmol.com/compound/(5e)-7-oxozeaenol |
Additional Information | https://www.targetmol.com/datasheet/T35438 |