Gedatolisib (PKI-587)
Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2.
| Trivial name | PF-05212384 |
| Catalog Number | S2628 |
| Molecular Formula | C26H44O4 |
| CAS# | 1197160-78-3 |
| Inchi | InChI=1S/C26H44O4/c1-5-17-21-14-16(27)10-12-26(21,4)20-11-13-25(3)18(15(2)6-9-22(28)29)7-8-19(25)23(20)24(17)30/h15-21,23-24,27,30H,5-14H2,1-4H3,(H,28,29)/t15-,16-,17-,18-,19?,20?,21+,23?,24-,25-,26-/ m1/s1 |
| Inchi Key | ZXERDUOLZKYMJM-AMGBFIHRSA-N |
| SMILES | CCC1C2CC(CCC2(C3CCC4(C(C3C1O)CCC4C(C)CCC(=O)O)C)C)O |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pki587.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PKI-587-chemical-structure-s2628.gif |
