Dabrafenib Mesylate

Dabrafenib Mesylate (GSK2118436) is the mesylate salt form of dabrafenib, an orally bioavailable inhibitor of B-raf (BRAF) protein with IC50s of 0.8 nM, 3.2 nM and 5 nM for B-Raf (V600E), B-Raf (WT) and C-Raf, respectively.

Price Not Available 25mg Dabrafenib Mesylate Supplier Page

Trivial name	GSK2118436 Mesylate
Catalog Number	S5069
Molecular Formula	C23H20F3N5O2S2.CH4O3S
CAS#	1195768-06-9
Inchi	InChI=1S/C23H20F3N5O2S2.CH4O3S/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25;1-5(2,3)4/h4-11,31H,1-3H3,(H2,27,28,29);1H3,(H,2,3,4)
Inchi Key	YKGMKSIHIVVYKY-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=NC(=C(S1)C2=NC(=NC=C2)N)C3=C(C(=CC=C3)NS(=O)(=O)C4=C(C=CC=C4F)F)F.CS(=O)(=O)O
Size	25mg
Supplier Page	http://www.selleckchem.com/products/dabrafenib-mesylate.html
Additional Information	https://file.selleck.cn/downloads/struct/dabrafenib-mesylate-chemical-structure-s5069.gif