CZC-25146
CZC-25146 is a potent and selective LRRK2 inhibitor with IC50 of 4.76 nM and 6.87 nM for human wild type LRRK2 and G2019S LRRK2, respectively.
Trivial name | N/A |
Catalog Number | S2002 |
Molecular Formula | C22H25FN6O4S |
CAS# | 1191911-26-8 |
Inchi | InChI=1S/C22H25FN6O4S/c1-32-20-13-15(29-9-11-33-12-10-29)7-8-19(20)26-22-24-14-16(23)21(27-22)25-17-5-3-4-6-18(17)28-34(2,30)31/h3-8,13-14,28H,9-12H2,1-2H3,(H2,24,25,26,27) |
Inchi Key | XXHHOTZUJIXPJX-UHFFFAOYSA-N |
SMILES | COC1=C(C=CC(=C1)N2CCOCC2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NS(=O)(=O)C)F |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/czc-25146.html |
Additional Information | https://file.selleck.cn/downloads/struct/czc-25146-chemical-structure-s2002.gif |