B-Raf inhibitor 1 (Compound 13) dihydrochloride
B-Raf inhibitor 1 (Compound 13) is a type IIA Raf inhibitor which bind to the DFG-out conformation with ki of 1 nM,1 nM,and 0.3 nM for B-Raf(WT), B-Raf(V600E) and C-Raf, respectively.
| Trivial name | N/A |
| Catalog Number | S6660 |
| Molecular Formula | C26H21Cl3N8 |
| CAS# | 1191385-19-9 |
| Inchi | InChI=1S/C26H19ClN8.2ClH/c1-15-4-9-19-18(10-12-29-24(19)34-17-7-5-16(27)6-8-17)21(15)35-25-20(3-2-11-28-25)22-23-26(32-13-30-22)33-14-31-23;;/h2-14H,1H3,(H,28,35)(H,29,34)(H,30,31,32,33);2*1H |
| Inchi Key | HRLQRNBAJCQMMG-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC=C(C=C3)Cl)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6.Cl.Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/b-raf-inhibitor-1-dihydrochlorid.html |
| Additional Information | https://file.selleck.cn/downloads/struct/b-raf-inhibitor-1-dihydrochloride-chemical-structure-s6660.gif |