TM5441
TM5441 is an orally bioavailable inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 ranging between 9.7 μM and 60.3 μM. TM5441 induces intrinsic apoptosis in several human cancer cell lines.
| Trivial name | N/A |
| Catalog Number | S6778 |
| Molecular Formula | C21H17ClN2O6 |
| CAS# | 1190221-43-2 |
| Inchi | InChI=1S/C21H17ClN2O6/c22-15-4-5-18(17(9-15)21(27)28)24-20(26)12-30-11-19(25)23-16-3-1-2-13(8-16)14-6-7-29-10-14/h1-10H,11-12H2,(H,23,25)(H,24,26)(H,27,28) |
| Inchi Key | BGGMLMAPVODXAU-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC(=C1)NC(=O)COCC(=O)NC2=C(C=C(C=C2)Cl)C(=O)O)C3=COC=C3 |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/tm5441.html |
| Additional Information | https://file.selleck.cn/downloads/struct/tm5441-chemical-structure-s6778.gif |