Trametinib DMSO solvate
Trametinib DMSO solvate is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assay. Trametinib activates autophagy and induces apoptosis.
Trivial name | GSK1120212, JTP-74057 |
Catalog Number | S4484 |
Molecular Formula | C28H29FIN5O5S |
CAS# | 1187431-43-1 |
Inchi | #N/A |
Inchi Key | #N/A |
SMILES | CN1C(=O)C(=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC4=C(F)C=C(I)C=C4)C5=CC=CC(=C5)NC(C)=O)C.C[S](C)=O |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/trametinib-dmso-solvate.html |
Additional Information | https://file.selleck.cn/downloads/struct/s4484-trametinib-dmso-solvate-chemical-structure.gif |