Trametinib Dimethyl Sulfoxide

Trametinib Dimethyl Sulfoxide is a MEK inhibitor used for melanoma.

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Catalog Number API0232622
Alternative Name(s) TRAMETINIB DIMETHYL SULFOXIDE; Trametinib DMSO; GSK1120212B
Research Area API
Molecular Formula C28H29FIN5O5S
CAS# 1187431-43-1
Inchi InChI=1S/C26H23FIN5O4.C2H6OS/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34;1-4(2)3/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34);1-2H3
Inchi Key OQUFJVRYDFIQBW-UHFFFAOYSA-N
SMILES CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5.CS(=O)C
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Trametinib dimethyl sulfoxide

Used for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment. It has a role as an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor.

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Catalog Number API1187431431
Alternative Name(s) Trametinib DMSO solvate TRAMETINIB DIMETHYL SULFOXIDE Trametinib DMSO Trametinib (DMSO solvate)
Research Area Anti-Tumor APIs
Molecular Formula C28H29FIN5O5S
CAS# 1187431-43-1
SMILES CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5.CS(=O)C
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Supplier Page https://www.protheragen.ai/trametinib-dimethyl-sulfoxide-item-11878.html