Evacetrapib (LY2484595)
Evacetrapib (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3.
Trivial name | N/A |
Catalog Number | S2925 |
Molecular Formula | C31H36F6N6O2 |
CAS# | 1186486-62-3 |
Inchi | InChI=1S/C31H36F6N6O2/c1-18-11-19(2)27-25(12-18)26(5-4-10-42(27)16-20-6-8-22(9-7-20)28(44)45)43(29-38-40-41(3)39-29)17-21-13-23(30(32,33)34)15-24(14-21)31(35,36)37/h11-15,20,22,26H,4-10,16-17H2,1-3H3, (H,44,45)/t20-,22-,26-/m0/s1 |
Inchi Key | IHIUGIVXARLYHP-YBXDKENTSA-N |
SMILES | CC1=CC(=C2C(=C1)C(CCCN2CC3CCC(CC3)C(=O)O)N(CC4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)C5=NN(N=N5)C)C |
Size | 5mg |
Supplier Page | http://www.selleckchem.com/products/evacetrapib-ly2484595.html |
Additional Information | https://file.selleck.cn/downloads/struct/Evacetrapib-LY-2484595-chemical-structure-s2925.jpg |