BMS-794833
BMS-794833 is a potent ATP competitive inhibitor of Met (c-Met)/VEGFR2 with IC50 of 1.7 nM/15 nM, also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2201 |
| Molecular Formula | C23H15ClF2N4O3 |
| CAS# | 1174046-72-0 |
| Inchi | InChI=1S/C23H15ClF2N4O3/c24-20-19(7-8-29-22(20)27)33-18-6-5-14(9-17(18)26)30-23(32)16-11-28-10-15(21(16)31)12-1-3-13(25)4-2-12/h1-11H,(H2,27,29)(H,28,31)(H,30,32) |
| Inchi Key | PDYXPCKITKHFOZ-UHFFFAOYSA-N |
| SMILES | C1=CC(=CC=C1C2=CNC=C(C2=O)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/BMS-794833.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BMS-794833-chemical-structure-S2201.gif |