BMS-794833
BMS-794833 is a potent ATP competitive inhibitor of Met (c-Met)/VEGFR2 with IC50 of 1.7 nM/15 nM, also inhibits Ron, Axl and Flt3 with IC50 of <3 nM; a prodrug of BMS-817378. Phase 1.
| Trivial name | N/A |
| Catalog Number | S2201 |
| Molecular Formula | C27H27N5 |
| CAS# | 1174046-72-0 |
| Inchi | InChI=1S/C27H27N5/c1-31-10-12-32(13-11-31)18-19-2-4-20(5-3-19)23-15-24-25(17-30-27(24)29-16-23)21-6-7-26-22(14-21)8-9-28-26/h2-9,14-17,28H,10-13,18H2,1H3,(H,29,30) |
| Inchi Key | QKKIWEILHCXECO-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)CC2=CC=C(C=C2)C3=CC4=C(NC=C4C5=CC6=C(C=C5)NC=C6)N=C3 |
| Size | 50mg |
| Supplier Page | http://www.selleckchem.com/products/BMS-794833.html |
| Additional Information | https://file.selleck.cn/downloads/struct/BMS-794833-chemical-structure-S2201.gif |