PKI-402
PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3Kα/β/γ/δ and mTOR with IC50 of 2 nM/7 nM/16 nM/14 nM and 3 nM, respectively; also potent to PI3Kα mutants E545K and H1047R.
| Trivial name | N/A |
| Catalog Number | S2739 |
| Molecular Formula | C29H34N10O3 |
| CAS# | 1173204-81-3 |
| Inchi | InChI=1S/C29H34N10O3/c1-3-39-27-24(34-35-39)26(37-16-18-42-19-17-37)32-25(33-27)20-4-8-22(9-5-20)30-29(41)31-23-10-6-21(7-11-23)28(40)38-14-12-36(2)13-15-38/h4-11H,3,12-19H2,1-2H3,(H2,30,31,41) |
| Inchi Key | ZAXFYGBKZSQBIV-UHFFFAOYSA-N |
| SMILES | CCN1C2=C(C(=NC(=N2)C3=CC=C(C=C3)NC(=O)NC4=CC=C(C=C4)C(=O)N5CCN(CC5)C)N6CCOCC6)N=N1 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pki-402.html |
| Additional Information | https://file.selleck.cn/downloads/struct/PKI-402-chemical-structure-s2739.gif |