U0126-EtOH
U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059. U0126 inhibits autophagy and mitophagy with antiviral activity.
| Trivial name | N/A |
| Catalog Number | S1102 |
| Molecular Formula | C18H16N6S2.C2H6O |
| CAS# | 1173097-76-1 |
| Inchi | InChI=1S/C18H16N6S2.C2H6O/c19-9-11(17(23)25-15-7-3-1-5-13(15)21)12(10-20)18(24)26-16-8-4-2-6-14(16)22;1-2-3/h1-8H,21-24H2;3H,2H2,1H3/b17-11-,18-12-; |
| Inchi Key | CFQULUVMLGZVAF-YIQLKAPXSA-N |
| SMILES | CCO.C1=CC=C(C(=C1)N)SC(=C(C#N)C(=C(N)SC2=CC=CC=C2N)C#N)N |
| Size | 25mg |
| Supplier Page | http://www.selleckchem.com/products/U0126.html |
| Additional Information | https://file.selleck.cn/downloads/struct/u0126-etoh-chemical-structure-s1102.gif |