(3a’S,4’R,5’R,6a’R)-5′-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2′(1’H)-pentalene]-4′-carboxamide

(3a’S,4’R,5’R,6a’R)-5′-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]hexahydro-N-[(1R)-2-hydroxy-1-phenylethyl]-5,5-dimethyl-spiro[1,3-dioxane-2,2′(1’H)-pentalene]-4′-carboxamide is an intermediate in the synthesis of Iloprost (I267300),a synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, raynaud’s phenomenon and ischemia.

Catalog Number BB066999
Alternative Name(s) (3a'S,4'R,5'R,6a'R)-5'-((tert-Butyldimethylsilyl)oxy)-N-((S)-2-hydroxy-1-phenylethyl)-5,5-dimethylhexahydro-1'H-spiro[[1,3]dioxane-2,2'-pentalene]-4'-carboxamide
Molecular Formula C28H45NO5Si
CAS# 116855-81-3
Inchi InChI=1S/C28H45NO5Si/c1-26(2,3)35(6,7)34-23-13-20-14-28(32-17-27(4,5)18-33-28)15-21(20)24(23)25(31)29-22(16-30)19-11-9-8-10-12-19/h8-12,20-24,30H,13-18H2,1-7H3,(H,29,31)/t20-,21+,22-,23-,24-/m1/s1
Inchi Key RFODHSIIJZKRDJ-KEJFTWOCSA-N
Size Please inquire
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