GDC-0623
GDC-0623 (G-868) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
| Trivial name | G-868 |
| Catalog Number | S7553 |
| Molecular Formula | C16H14FIN4O3 |
| CAS# | 1168091-68-6 |
| Inchi | InChI=1S/C16H14FIN4O3/c17-13-7-10(18)1-4-14(13)20-15-12(16(24)21-25-6-5-23)3-2-11-8-19-9-22(11)15/h1-4,7-9,20,23H,5-6H2,(H,21,24) |
| Inchi Key | RFWVETIZUQEJEF-UHFFFAOYSA-N |
| SMILES | C1=CC(=C(C=C1I)F)NC2=C(C=CC3=CN=CN32)C(=O)NOCCO |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/gdc-0623.html |
| Additional Information | https://file.selleck.cn/downloads/struct/gdc0623-chemical-structure-s7553.gif |