Pyr3
Pyr3 is a selective and potent inhibitor of transient receptor potential canonical channel 3 (TRPC3). It inhibits TRPC3-mediated Ca2+ influx in a dose-dependent manner with the IC50 value of 0.7 μM. It holds potential for treating TRPC3-related diseases like cardiac hypertrophy.
| Catalog Number | E4659 |
| Molecular Formula | C29H31ClFN5O5 |
| CAS# | 1160514-60-2 |
| SMILES | COC1=CC(=CC(=C1)C(CO)NC(=O)C(C)N2CC3=CC=C(C=C3C2=O)C4=NC(=NC=C4Cl)NC5CCOCC5)F |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/pyr3.html |
| Additional Information | https://file.selleck.cn/downloads/struct/E4659-Pyr3-chemical-structure.png |