CZC24832
CZC24832 is the first selective PI3Kγ inhibitor with IC50 of 27 nM, with 10-fold selectivity over PI3Kβ and >100-fold selectivity over PI3Kα and PI3Kδ.
Trivial name | N/A |
Catalog Number | S7018 |
Molecular Formula | C15H17FN6O2S |
CAS# | 1159824-67-5 |
Inchi | InChI=1S/C15H17FN6O2S/c1-15(2,3)21-25(23,24)11-4-9(6-18-7-11)10-5-12(16)13-19-14(17)20-22(13)8-10/h4-8,21H,1-3H3,(H2,17,20) |
Inchi Key | RXRZPHQBTHQXSV-UHFFFAOYSA-N |
SMILES | CC(C)(C)NS(=O)(=O)C1=CN=CC(=C1)C2=CN3C(=NC(=N3)N)C(=C2)F |
Size | 50mg |
Supplier Page | http://www.selleckchem.com/products/czc24832.html |
Additional Information | https://file.selleck.cn/downloads/struct/CZC24832-chemical-structure-s7018.gif |