Avagacestat (BMS-708163)

Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.

Price Not Available 50mg Avagacestat (BMS-708163) Supplier Page

Trivial name	N/A
Catalog Number	S1262
Molecular Formula	C21H15F2N3O3S
CAS#	1146699-66-2
Inchi	InChI=1S/C21H15F2N3O3S/c22-16-9-17(23)11-19(10-16)30(28,29)18-4-1-14(2-5-18)12-25-21(27)15-3-6-20-24-7-8-26(20)13-15/h1-11,13H,12H2,(H,25,27)
Inchi Key	XRDVXQQZLHVEQZ-UHFFFAOYSA-N
SMILES	C1=CC(=CC=C1CNC(=O)C2=CN3C=CN=C3C=C2)S(=O)(=O)C4=CC(=CC(=C4)F)F
Size	50mg
Supplier Page	http://www.selleckchem.com/products/BMS-708163.html
Additional Information	https://file.selleck.cn/downloads/struct/BMS-708163-chemical-structure-S1262.gif