SNS-314 Mesylate

SNS-314 Mesylate is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively and less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2.

Price Not Available 5mg SNS-314 Mesylate Supplier Page
Trivial name N/A
Catalog Number S8699
Molecular Formula C18H15ClN6OS2.CH4O3S
CAS# 1146618-41-8
Inchi InChI=1S/C18H15ClN6OS2/c19-11-2-1-3-12(8-11)24-17(26)25-18-21-9-13(28-18)4-6-20-16-15-14(5-7-27-15)22-10-23-16/h1-3,5,7-10H,4,6H2,(H,20,22,23)(H2,21,24,25,26)
Inchi Key FAYAUAZLLLJJGH-UHFFFAOYSA-N
SMILES CS(=O)(=O)O.C1=CC(=CC(=C1)Cl)NC(=O)NC2=NC=C(S2)CCNC3=NC=NC4=C3SC=C4
Size 5mg
Supplier Page http://www.selleckchem.com/products/sns-314.html
Additional Information https://file.selleck.cn/downloads/struct/sns-314-mesylate-chemical-structure-s8699.gif

SNS-314

SNS-314 is a potent and selective inhibitor of Aurora A, Aurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1.

Price Not Available 5mg SNS-314 Supplier Page
Trivial name N/A
Catalog Number S1154
Molecular Formula C18H15ClN6OS2
CAS# 1057249-41-8
Inchi InChI=1S/C18H15ClN6OS2.CH4O3S/c19-11-2-1-3-12(8-11)24-17(26)25-18-21-9-13(28-18)4-6-20-16-15-14(5-7-27-15)22-10-23-16;1-5(2,3)4/h1-3,5,7-10H,4,6H2,(H,20,22,23)(H2,21,24,25,26);1H3,(H,2,3,4)
Inchi Key FYCODPVDEFFWSR-UHFFFAOYSA-N
SMILES C1=CC(=CC(=C1)Cl)NC(=O)NC2=NC=C(S2)CCNC3=NC=NC4=C3SC=C4
Size 5mg
Supplier Page http://www.selleckchem.com/products/sns-314-mesylate.html
Additional Information https://file.selleck.cn/downloads/struct/sns-314-chemical-structure-s1154.gif