WYE-125132 (WYE-132)
WYE-125132 (WYE-132) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.
| Trivial name | N/A |
| Catalog Number | S2661 |
| Molecular Formula | C27H33N7O4 |
| CAS# | 1144068-46-1 |
| Inchi | InChI=1S/C27H33N7O4/c1-28-26(35)30-18-4-2-17(3-5-18)23-31-24(33-15-20-6-7-21(16-33)38-20)22-14-29-34(25(22)32-23)19-8-10-27(11-9-19)36-12-13-37-27/h2-5,14,19-21H,6-13,15-16H2,1H3,(H2,28,30,35) |
| Inchi Key | QLHHRYZMBGPBJG-UHFFFAOYSA-N |
| SMILES | CNC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCC5(CC4)OCCO5)C(=N2)N6CC7CCC(C6)O7 |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/wye-125132.html |
| Additional Information | https://file.selleck.cn/downloads/struct/WYE125132-chemical-structure-s2661.gif |