PF-8380
PF-8380 is a potent autotaxin (ATX) inhibitor with IC50 of 2.8 nM in an in vitro enzyme assay.
| Trivial name | N/A |
| Catalog Number | S8218 |
| Molecular Formula | C22H21Cl2N3O5 |
| CAS# | 1144035-53-9 |
| Inchi | InChI=1S/C22H21Cl2N3O5/c23-16-9-14(10-17(24)12-16)13-31-22(30)27-7-5-26(6-8-27)4-3-19(28)15-1-2-18-20(11-15)32-21(29)25-18/h1-2,9-12H,3-8,13H2,(H,25,29) |
| Inchi Key | JMSUDQYHPSNBSN-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1CCC(=O)C2=CC3=C(C=C2)NC(=O)O3)C(=O)OCC4=CC(=CC(=C4)Cl)Cl |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/pf-8380.html |
| Additional Information | https://file.selleck.cn/downloads/struct/pf-8380-chemical-structure-s8218.gif |