Pidnarulex (CX-5461)

Pidnarulex (CX-5461) is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116, A375, and MIA PaCa-2 cells, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation.

Price Not Available 5mg Pidnarulex (CX-5461) Supplier Page

Trivial name	N/A
Catalog Number	S2684
Molecular Formula	C27H27N7O2S
CAS#	1138549-36-6
Inchi	InChI=1S/C27H27N7O2S/c1-17-14-29-18(15-28-17)16-30-26(36)23-24(35)19-8-9-22(33-11-5-10-32(2)12-13-33)31-25(19)34-20-6-3-4-7-21(20)37-27(23)34/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3,(H,30,36)
Inchi Key	XGPBJCHFROADCK-UHFFFAOYSA-N
SMILES	CC1=CN=C(C=N1)CNC(=O)C2=C3N(C4=CC=CC=C4S3)C5=C(C2=O)C=CC(=N5)N6CCCN(CC6)C
Size	5mg
Supplier Page	http://www.selleckchem.com/products/cx-5461.html
Additional Information	https://file.selleck.cn/downloads/struct/CX-5461-chemical-structure-s2684.gif