Pidnarulex (CX-5461)

Pidnarulex (CX-5461) is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116, A375, and MIA PaCa-2 cells, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation.

Price Not Available 50mg Pidnarulex (CX-5461) Supplier Page

Trivial name	N/A
Catalog Number	S2684
Molecular Formula	C13H10Cl3N5
CAS#	1138549-36-6
Inchi	InChI=1S/C13H9Cl2N5.ClH/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;/h1-7H,8H2;1H
Inchi Key	MBTJFFMIPPMRGR-UHFFFAOYSA-N
SMILES	C1=CC(=C(C(=C1)Cl)Cl)C2=NN=NN2CC3=CN=CC=C3.Cl
Size	50mg
Supplier Page	http://www.selleckchem.com/products/cx-5461.html
Additional Information	https://file.selleck.cn/downloads/struct/CX-5461-chemical-structure-s2684.gif