Donafenib (Sorafenib D3)
Donafenib (Sorafenib D3, Bay 43-9006 D3, CM-4307) is the deuterium labeled Sorafenib. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 15 nM, 20 nM and 22 nM for Raf-1, mVEGFR-2, mVEGFR-3 and B-RAF, respectively.
| Trivial name | Bay 43-9006 D3, CM-4307 |
| Catalog Number | S9621 |
| Molecular Formula | C21H13D3ClF3N4O3 |
| CAS# | 1130115-44-4 |
| SMILES | CNC(=O)C1=NC=CC(=C1)OC2=CC=C(C=C2)NC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F |
| Size | 10mM/1mL |
| Supplier Page | http://www.selleckchem.com/products/donafenib-sorafenib-d3.html |
| Additional Information | https://file.selleck.cn/downloads/struct/s9621-donafenib-chemical-structure.gif |