Dynole 34-2
Dynole 34-2 is a dynamin GTPase inhibitor (IC50s=6.9 and 14.2 µM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis, as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME).
| Catalog Number | E7699 |
| Molecular Formula | C18H19N3O3S.HCl |
| CAS# | 1128165-88-7 |
| Inchi | InChI=1S/C18H19N3O3S.ClH/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;/h2-9,15H,10-12H2,1H3,(H,20,22,23);1H |
| Inchi Key | XRSCTTPDKURIIJ-UHFFFAOYSA-N |
| SMILES | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.Cl |
| Size | 5mg |
| Supplier Page | http://www.selleckchem.com/products/dynole-34-2.html |
| Additional Information | https://file.selleck.cn/downloads/struct/e7699-dynole-34-2-chemical-structure-tube.png |